In Vivo Stability and Biodistribution of Quantum Dots by Inductively Coupled Plasma-Atomic Emission Spectrometry

Abstract:

Here we studied in vivo stability and biodistribution of quantum dots. Their distribution in vivo at various time points were determined by measuring the amount of cadmium ions and selenium ions in various organs by inductively coupled plasma-atomic emission spectrometry. The amount of cadmium ions was higher in liver than in other organs at all times. The amount of cadmium ions in kidney and spleen were increased gradually in time-dependent. There are also obviously increased cadmium ions in lung and heart at all times compared to the control. However the amount of selenium ions was high in all organs except for brain before the 3rd day.

• Periodical: Advanced Materials Research (Volume 412)
• Pages: 449-452
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.412.449
• Online since: November 2011
• Authors: Chun Li Hao
• Keywords: Biodistribution, ICP-AES, Quantum Dot (QD)

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