Preparation of Controlled-Release Tablets of Sasanquasaponin Using Broomcorn-Stalk and its Performance

Xiao Zhen Liu; Yue Xing Song; Zhong Fang Lai; Ling Ling Guo; Ling Ling Song

doi:10.4028/www.scientific.net/AMR.413.304

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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 413Preparation of Controlled-Release Tablets of...

Preparation of Controlled-Release Tablets of Sasanquasaponin Using Broomcorn-Stalk and its Performance

Abstract:

The controlled-release tablets of sasanquasaponin (SQS) were prepared by using SQS, broomcorn-stalk and lactose as the main drug and accessories. The effect of the particle size of broomcorn-stalk on release rate was studied. Kinetics equation of the controlled-release tablets of SQS releasing SQS was fitted. The thermal stability and wet stability of the controlled-release tablets of SQS were investigated. The controlled-release tablet of SQS was characterized by infrared absorption spectrum (IR) techniques. The releasing rate of the controlled-release tablets of SQS were controlled by controlling the particle size of broomcorn-stalk. Release speeds of the controlled-release tablets of SQS releasing SQS were constant. The thermal stability and wet stability of the controlled-release tablets of SQS were good. The chemical bonds were formed among SQS, broomcorn-stalk and lactose.

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Periodical:

Advanced Materials Research (Volume 413)

Pages:

304-307

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.413.304

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Online since:

December 2011

Authors:

Xiao Zhen Liu, Yue Xing Song, Zhong Fang Lai, Ling Ling Guo, Ling Ling Song

Keywords:

Broomcorn-Stalk, Controlled-Release, Lactose, Release Rate, Sasanquasaponin

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