Retard of D-Galactose-Induced Aging in Mice by Whey Hydrolysates

Jing Liu; Ying Miao; Zheng Zhao

doi:10.4028/www.scientific.net/AMR.415-417.43

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 415-417Retard of D-Galactose-Induced Aging in Mice by...

Retard of D-Galactose-Induced Aging in Mice by Whey Hydrolysates

Abstract:

The antioxidant capacities and anti-aging properties of whey hydrolysates fermented by Lactobacillus plantarum TUST200209 and its purified whey peptides were studied, which were dose-dependent and category-dependent. The treatment groups were orally administered high dose (1.5g/kg/day) and low dose (0.5/kg/day) of whey hydrosyates and its purified peptides, and high dose (1.5g/kg/day) of 0.9% saline (vehicle group and aged model group) and mixture of whey and Lactobacillus plantarum TUST200209 in senescence accelerated Kunming mice for six weeks, respectively. Whey hydrolysates and its purified peptides could increase levels of superoxide dismutase, glutathione peroxidase, and decrease contents of malondialdehyde in serum, quadriceps femoris and mitochondria, and for the high dose of whey peptides, most of the increase was significant (P＜0.05) compared with vehicle group. It demonstrated that the whey hydrolysates could significantly retard aging of the mice induced by free radical, especially for its purified peptides.

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Periodical:

Advanced Materials Research (Volumes 415-417)

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43-46

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https://doi.org/10.4028/www.scientific.net/AMR.415-417.43

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Online since:

December 2011

Authors:

Jing Liu, Ying Miao, Zheng Zhao

Keywords:

Anti-Aging, Antioxidant Capacity, Whey Hydrolysates, Whey Peptides

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