Morphology and Structure Properties of PEG-b-PBT, PEG-b-PBT-HA Nanofibers Based Gas-Electrospun

Abstract:

The block copolymer solutions were prepared by dissolving polyethylene glycol/polybutylene terephthalate (PEG-b-PBT) with different intrinsic viscosities in chloroform. The composite ultrafine nanofibers of PEG-b-PBT and PEG-b-PBT-HA(hydroxyapatite) were obtained by gas-electrospun, and were characterized by scanning electron microscopy (SEM), horizontal attenuated total reflectance for Fourier transform infrared spectrometer (HATR-FTIR), dynamic contact angle measuring apparatus and differential scanning calorimetry (DSC). The gas-electrospun fibrous membranes, which were made of ultrafine fibers with average diameter 180-1200nm and well-interconnected pores, were possessed with high surface-to-volume ratio and excellent hydrophilicity. The above results strongly suggest that fibrous membranes combine advantages of synthetic biodegradable polymers and nanometer-scale dimension for mimicking the natural ECM, and may represent an ideal tissue engineering scaffold, particularly for soft tissue, such as skin and cartilage tissue engineering scaffold.

• Periodical: Advanced Materials Research (Volumes 430-432)
• Pages: 894-897
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.430-432.894
• Online since: January 2012
• Authors: Xiao Zhan Yang, Zhen Sheng Li, Ji Ning Gao, Li Long Zhang
• Keywords: Fibrous Membranes, Gas-Electrospun, HA, PEG-b-PBT, Tissue Engineering

References

[1] C. D. Ranjna, K. D. Aroop: Biotechnology Advances Vol 28 (2010), pp.764-769.

[2] H. H. Sepideh, S. L. Katja, P. D. Andrew et al.: Biomaterials Vol 29 (2008), pp.2907-2914.

[3] L. Moroni, R. Licht, J. de Boer et al.: Biomaterials Vol 27 (2006), pp.4911-4922.

[4] L. Qing, J. R. de Wijn, C. A. van Blitterswijk: Biomaterials Vol 18 (1997), pp.1263-1270.

[5] C. Subramanian, R.A. Weiss, M.T. Shawa: Polymer Vol 51 (2010), p.1983-(1989).

[6] A. B. Bryan, T. Ajay, M. A. Joel et al.: Biomaterials Vol 32 (2011), pp.1583-1590.