Investigation of Sodium Hyaluronate/ Konjac Glucomannan Blend Films

Jia Chen; Jing Wang; Xiao Pei Wu; Qing Hua Chen

doi:10.4028/www.scientific.net/AMR.510.673

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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 510Investigation of Sodium Hyaluronate/ Konjac...

Investigation of Sodium Hyaluronate/ Konjac Glucomannan Blend Films

Abstract:

The blend films were fabricated via blending sodium hyaluronate (SH) and Konjac glucomannan (KGM). Lactic acid was applied as modifier and the mixture of Ammonia and anhydrous alcohol as cross-linker. The influencing factors were analyzed via the orthogonal experiment L16(4,5). It was shown that the water absorption of the blend films was around 151%~608%. Tensile strength and elongation of the blend film samples reached about 11.3~20.7MPa and 10.8~20.2% respectively. The degradation rate declined obviously compared with the simple use of the SH. XRD and IR spectra indicated that crystallinity of the blend films was enhanced slightly after cross-linking. The blend films were co-cultured with bone mesenchymal stem cells. It was demonstrated that the films could support the growth of cells and were non-toxicity and good biocompatibility.

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Periodical:

Advanced Materials Research (Volume 510)

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673-678

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.510.673

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Online since:

April 2012

Authors:

Jia Chen, Jing Wang, Xiao Pei Wu, Qing Hua Chen

Keywords:

Anti-Blocking Films, Degradation, Konjac Glucomannan, Lactic Acid, Sodium Hyaluronate

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