Nonlinear Analysis of EEG Using Fractal Dimension and Approximate Entropy

Abstract:

The automated detection of seizures in EEG is significant for epilepsy monitoring, diagnosis and rehabilitation. In this work, we evaluated the differences between epileptic EEG, interictal EEG and normal EEG by computing their Higuchi Fractal Dimension (HFD) and Approximate Entropy (ApEn). The calculated results show that there are significant differences between epileptic EEG and normal EEG in the variations of HFD and ApEn. HFD and ApEn have been shown to be useful to characterize normal and epileptic brain electrical activities, and the degree of complexity of epileptic EEG is lower than that of normal EEG even during interictal time. Our results could be helpful for interpreting the epileptic brain electrical activity and the normal brain electrical activity, and their neurodynamics.

• Periodical: Advanced Materials Research (Volumes 532-533)
• Pages: 988-992
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.532-533.988
• Online since: June 2012
• Authors: Shu Juan Geng, Wei Dong Zhou, Qing Mei Yao, Zhen Ma
• Keywords: Approximate Entropy, EEG, Epilepsy, Fractal Dimension

References

[1] R. G. Andrzejak, K. Lehnertz, F. Mormann, C. Rieke, P. David, and E. E. Christian: submitted to Phys Rev E, (2001).

[2] M. P. Dafilis, T. J. L. David, and P J Cadusch: submitted to Chaos, (2001).

[3] P. A. Robinson, C. J. Rennie, and D. L. Rowe: submitted to Phys Rev E, (2002).

[4] C. J. Stam: submitted to Clinical Neurophysiology, (2005).

[5] K. Natarajan, U. Acharya, F. Alias, et al.: submitted to BioMedical Engineering OnLine, (2004).

[6] C. Yamaguchi: submitted to Memoirs of Fukui University of Technology, (2003).

[7] A. Babloyantz, J. M. Salazar, C. Nicolis: submitted to Physics Letters A, (1985).

[8] J. Ulbikas, A. Cenys: submitted to Nonlinear Analysis: Modelling and Control, (1998).

[9] J.P. Pijn, J. V. Neerven , A. Noest , et al.: submitted to Electroencephalogr Clin Neurophysiol, (1991).

[10] K.P. Harikrishnan, R. Misra, G. Ambika, and A.K. Kembhavi: submitted to Physica D, (2006).

[11] T. Higuchi: submitted to Physica D, (1988).

[12] M. Katz: submitted to Comput. Biol. Med., (1988).

[13] A. Accardo, M. Affinito, M. Carrozzi, and F. Bouquet: submitted to Biol. Cybern., (1997).

[14] C. Elger , K. Lehnertz: submitted to European J. Neuroscience, (1997).

[15] S. M. Pincus: submitted to Proceedings National Academy Sciences USA , (1991).

[16] S. M. Pincus: submitted to Proceedings National Academy Sciences USA, (1996).

[17] S. M. Pincus: submitted to Methods in Enzymology, (2000).