Using RAFT Polymerization to Synthesize Potential Drug/Gene Delivery System

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Abstract:

Biodegradable cationic micelles were prepared from P(PEGMEMA)-PDMAEMA-PCL-PDMAEMA-P(PEGMEMA) five blocks copolymers by reversible addition-fragmentation chain transfer (RAFT) polymerization with CPADB-PCL-CPADB (CPADB: 4-Cyanopentanoic acid dithiobenzoate; PCL: 5600 Da) as a macro-RAFT agent. These five blocks copolymers formed nano-sized micelles in water.

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Periodical:

Advanced Materials Research (Volumes 535-537)

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1079-1082

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June 2012

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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