Synthesis, Characterized and Biological Activities of Chalcone Derivatives

Xiao Yang Qiu; Su Zhi Li; An Ran Shi; Qiao Li Yue

doi:10.4028/www.scientific.net/AMR.535-537.2540

Paper Titles

Effect of Applied Voltage on Polymer Aggregation in Electrospraying of Thermoplastic Polymer
p.2522

Study on the Characterization and Application of Poly-Silicate Magnesium Ferric Sulfate Borate (PFMSSB)
p.2526

First-Principles Investigation of ThO₂
p.2531

Study of Fibrous AlPO₄-5 via Hydrothermal Conditions: Morphology Evolution and Growth Mechanism
p.2535

Synthesis, Characterized and Biological Activities of Chalcone Derivatives
p.2540

Dielectric Characteristics of Hydrated Paraffin
p.2544

Predicting Impact Sensitivity of Heterocyclic Nitroarenes from Molecular Structures Selected by Genetic Algorithm
p.2550

Effect of BPR on the Preparation of Nb-Base Powder via Ball Milling
p.2554

The Influence of the Viscosity of Edible Ink to Ink-Jet Printing Drop State
p.2559

HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 535-537Synthesis, Characterized and Biological Activities...

Synthesis, Characterized and Biological Activities of Chalcone Derivatives

Abstract:

A series of 4-nitrochalcones (compounds 1-10) are synthesized and characterized. The products synthesized are evaluated for their cytotoxic activities in vitro. Among the compounds tested, (E)-3-(4-nitrophenyl)-1-(4-nitrophenyl)prop-2-en-1-one (1) showes the favorable in vitro cytotoxic activity against human nasopharyngeal epidermoid tumor cell line KB.

You might also be interested in these eBooks

View Preview

Info:

Periodical:

Advanced Materials Research (Volumes 535-537)

Pages:

2540-2543

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.535-537.2540

Citation:

Cite this paper

Online since:

June 2012

Authors:

Xiao Yang Qiu, Su Zhi Li, An Ran Shi, Qiao Li Yue

Keywords:

Chalcone Derivative, Cytotoxic Activity, Structure-Activity Relationship

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

References

[1] G.S. Viana, M.A. Bandeira and F. J. Mtos: Phytomedicine Vol. 10 (2003), p.189

Google Scholar

[2] H.K. Hsieh, T.H. Lee, J.P. Wang, J.J. Wang and C. N. Lin: Pharm. Res. Vol. 15 (1998), p.39

Google Scholar

[3] R. De Vineenzo, C. Ferlini, M. Distofano, C. Gaggini, A. Riva, E. Bombardelli, P. Morazzoni, P. Valenti, F. Belluti, F. D. Ranelletti, S. Mancuso and G. Scambia: Cancer Chemother Pharm. Vol. 46 (2000), p.305

DOI: 10.1007/s002800000160

Google Scholar

[4] S.K. Kumar, E. Hager, C. Peuttit, H. Gurulingappa, N.E. Davidson and S.R. Khan: J. Med. Chem. Vol. 46 (2003), p.2813

Google Scholar

[5] M. Liu, P. Wilairat and M.L. Go: J. Med. Chem. Vol. 44 (2001), p.4443

Google Scholar

[6] J.H. Wu, X.H. Wang and Y.H. Yi: Bioorg. Med. Chem. Let. Vol. 13 (2003), p.1813

Google Scholar

[7] X. Chen, C. Plasencia, Y. Hou and N. Neamati: J. Med. Chem. Vol. 48 (2005), p.1098

Google Scholar