Ultrastructural Characterization of Liposomes Using Transmission Electron Microscope

Abstract:

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A liposome is a spherical vesicle composed of phospholipids and cholesterol bilayer membrane and contains a core of aqueous solution. Liposomes are polymeric nanoparticles used for drug delivery due to their unique properties. It can carry both hydrophobic and hydrophilic molecules. In this study, we showed the benefit of using transmission electron microscope (TEM) with negative staining technique to investigate the morphology of liposomes produced by thin film method. At the same magnification of micrograph results, we could see the multilamellar vesicles of liposomes in various figures and different sizes.

Info:

Periodical:

Advanced Materials Research (Volumes 55-57)

Main Theme:

Edited by:

Tawee Tunkasiri

Pages:

709-711

DOI:

10.4028/www.scientific.net/AMR.55-57.709

Citation:

P. Chetanachan et al., "Ultrastructural Characterization of Liposomes Using Transmission Electron Microscope ", Advanced Materials Research, Vols. 55-57, pp. 709-711, 2008

Online since:

August 2008

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Price:

$35.00

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