Isolation of Zingiberene from Ginger Essential Oil by Two-Step Intermittent Silica Gel Column Chromatography

Yan Wang; Ai Ling Du; Ai Qin Du

doi:10.4028/www.scientific.net/AMR.550-553.1666

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 550-553Isolation of Zingiberene from Ginger Essential Oil...

Isolation of Zingiberene from Ginger Essential Oil by Two-Step Intermittent Silica Gel Column Chromatography

Abstract:

Zingiberene, one of the five major sesquiterpene hydrocarbon which are rich in ginger essential oil, is a natural antioxidant and serves as antiviral and antifertility agent. An efficient preparative isolation process of zingiberene from ginger essential oil has been developed in the present study. The separation experiments have been carried out on an intermittent silica gel column chromatography. After the first run treatment with the chromatography, the zingiberene content in the final product was increased from 35.11% to 60.41%. Afterwards the concentration was purified by using the second silica gel column chromatography. The recovery for the combined procedure was 70.68%, with a final purity 72.93%.Therefore, the separation can be achieved easily and efficiently via the intermittent silica gel column chromatography, and the method will provided a potential approach for large-scale separation and puriﬁcation of zingiberene for its wide pharmaceutical use.

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Periodical:

Advanced Materials Research (Volumes 550-553)

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1666-1670

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.550-553.1666

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Online since:

July 2012

Authors:

Yan Wang, Ai Ling Du, Ai Qin Du

Keywords:

Ginger Essential Oil, Isolation, Sesquiterpene Hydrocarbon, Silica Gel Column Chromatography, Zingiberene

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