Improved Preparation of 2,2-Dithiobis(Pyridine-N-Oxide)

Shu An Li; Run Lai Li; Zhen Ming Zhang; Kai Zhu; Guang Jie Wang

doi:10.4028/www.scientific.net/AMR.554-556.868

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Synthesis of Quaternary Ammonium Salt Cationic Surfactant with Long-Chain Alkyl and Epoxy Groups
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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 554-556Improved Preparation of...

Improved Preparation of 2,2-Dithiobis(Pyridine-N-Oxide)

Abstract:

2,2-Dithiobis(pyridine-N-oxide) (1) was prepared by reacting 2-pyridinethiol-N-oxide (2) and hydrogen peroxide-urea adduct (3) at the molar ratio of 1:1.25 and 45oC for 1.75h in high yield and purity of 91.6% and 99.6% respectively. The structures of product were characterized by IR, NMR.

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Periodical:

Advanced Materials Research (Volumes 554-556)

Pages:

868-873

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.554-556.868

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Online since:

July 2012

Authors:

Shu An Li, Run Lai Li, Zhen Ming Zhang, Kai Zhu, Guang Jie Wang

Keywords:

2,2'-Dithiobis(pyridine-N-Oxide), 2-Pyridinethiol-N-Oxide, Hydrogen Peroxide-Urea, Preparation

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References

[1] Nicholas G M, Blunt J W, Munro M H G. Cortamidine Oxide, a Novel Disulfide Metabolite from the New Zealand Basidiomycete (Mushroom) Cortinarius Species[J]. Journal of natural products, 2001, 64 (3):341–344.

DOI: 10.1021/np000408+

Google Scholar

[2] O'Donnell G, Poeschl R, Zimhony O, et al. Bioactive Pyridine-N-oxide Disulfides from Allium stipitatum[J]. Journal of Natural Products, 2009, 72 (3): 360–365.

DOI: 10.1021/np800572r

Google Scholar

[3] Bernstein J.,Losee K.A. Derivatives of 2-mercaptopyridine 1-oxide:US2742476[P]:1956-04-17.

Google Scholar

[4] Sandel B B, Dumas R H,Turley P A. Antimicrobial protection for plastic structures: US20050112339[P]:2005-05-26.

Google Scholar

[5] Duesseldorf A E, Hilden W S，Haan H H. Use of nanoscale active anti-dandruff ingredients:US20030003070[P]:2003-1-2.

Google Scholar

[6] Chen H. Study on PTS2 induced HeLa cell death and molecular mechanisms [D]. Nanjing：The specialization of biochemistry and molecular biology, Nanjing Normal University, 2007.

Google Scholar

[7] Zhang Y P, Fan L Y. TANG N,et al. Synthesis，Characterization and Antitumor Research of Tripicrate (2,2'-dithiobis(Pyridine-N-oxide))Rare Earth(III) Complexes [J]. Journal of Inorganic Chemistry，2001，17（3）：427-429.

Google Scholar

[8] Huang H. Protective effect of PTS2 on oleic acid induced acute lunginjury [D]. Nanjing：The specialization of physiology, Nanjing University, (2011)

Google Scholar