Effect of Bead Size on Fineness of Centella asiatica (C. asiatica) Particles in Wet Grinding

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Nanoparticles are now essential material to be used in material engineering, medicine and cosmetic application due to their chemical, mechanical and optical properties. Several experiments were designed to investigate the relationship effect of bead size using different bead size (4 mm and 2 mm) at fix grinding conditions. Changes in particles size produce were studied using dynamic light scattering method at 25 °C. The z-Average and polydipersity index for each particles size at different grinding were recorded. Using smaller size of zirconia bead will produced smaller size of C. asiatica than using larger bead size. As a result the smallest size particle by mean is 242 nm where 2,2-diphenyl-1-picrylhydrazyl (DPPH) inhibition at 517 nm shows the smaller particles has a higher percentage of inhibition.

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208-211

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October 2012

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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