Modeling, Analysis and Rapid Manufacturing of Customised Tibia Bone Scaffold

Abstract:

Bio Additive Manufacturing (BAM), an interdisciplinary field of Rapid Manufacturing (RM) and Tissue Engineering (TE), aims to manufacture the customised bone scaffold for bone replacement. The hydrodynamic stress induced in cells will depend not only on the culture medium flow rate, but also on the scaffold three- dimensional micro-architecture. This paper presents, the patient’s CT scan data in DICOM format is exported into MIMICS software to convert the 2D images into 3D IGES data. The customised bone scaffolds with pore size of 0.7mm and distance between adjacent edges of pores from 0.6mm to 1mm are created in modeling software (SOLIDWORKS 2011) and porosities of five customised bone scaffolds are determined. The above customised bone scaffolds are analysed in CFD software (ANSYS CFX) for the fluid density 1000 kg/m³ and viscosity 8.2 ×10^-4 kgm^-1 s^-1. The estimated Wall Shear Stress (WSS) at fluid velocities from 0.2mm/s to 1mm/s lies in the range of 7.05 x 10 ^-4 Pa to 43.4 x 10 ^-4 Pa., and these scaffolds are fabricated in Rapid Prototyping (RP) technique.

• Periodical: Advanced Materials Research (Volumes 622-623)
• Pages: 595-599
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.622-623.595
• Online since: December 2012
• Authors: Begum S. Rashia, G. Arumaikkannu, B. Ashiq
• Keywords: Bone Scaffold, Computational Fluid Dynamics (CFD), Pore Size, Porosity, Rapid Prototyping (RP), Wall Shear Stress (WSS)

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