Preparation and Characterization of Shellac/Polyvinylpyrrolidone Nanofiber as a Material for Medical Application

Article Preview

Abstract:

Nanofiber are defined as diameter less than 1 micron is under development for future medical application. The simple method was used to prepare a nonwoven in nanofiber of shellac (SHL) and polyvinylpyrrolidone (PVP) is electrospinning machine. The objective of the present study was to investigate the effect of electrospinning process on the physical properties. The SHL/ PVP nanofiber was prepared by dissolving in various rations of SHL/PVP in ethanol solution. Properties of obtained SHL/PVP nanofibers were elucidated. The results demonstrated that nanofibers of SHL/PVP were easily formed after spinning with diameter ranging from a few nanometers to several micrometers. SHL and PVP blended fiber could be formed by the hydrogen bonds attributing to the change in physicochemical properties via FT-IR. This study indicated that a simple method to create nanofiber nonwovens of multiple dissimilar composite polymers providing an approach for controlling diameter size distribution independently from fiber formation. Hence, the knowledge gained should support the development of the product for medical application in near future.

You might also be interested in these eBooks

Info:

Periodical:

Advanced Materials Research (Volumes 652-654)

Pages:

278-281

Citation:

Online since:

January 2013

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2013 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] S. Ramakrishna, F. Kazutoshi, T. Wee-Eong, L. Teik-Cheng, M. Zuwei, An introduction to electrospinning and nanofibers, World Scientific Publishing, Singapore, (2005) 275-339.

Google Scholar

[2] T. Thammachat, P.Sriamornsak, M. Luangtana-Anan, J.Nunthanid, C. Limmatvapirat, and S. Limmatvapirat1, Preparation and Characterization of Shellac Fiber as a Novel Material for Controlled Drug Release, Advanced Materials Research, 91 (2010) 1232-1235.

DOI: 10.4028/www.scientific.net/amr.152-153.1232

Google Scholar

[3] S. Limmatvapirat, C. Limmatvapirat, M. Luangtana-Anan, J. Nunthanid, T. Oguchi, Y. Tozuka, K. Yamamoto, S. Puttipipatkhachorn, Modification of physicochemical and mechanical properties of shellac by partial hydrolysis, Int. J. Pharm., 278 (2004) 41-49.

DOI: 10.1016/j.ijpharm.2004.02.030

Google Scholar

[4] S. Limmatvapirat, D. Panchapornpon, C. Limmatvapirat, J. Nunthanid, M. Luangtana-Anan, S. Puttipipatkhachorn, Formation of shellac succinate having improved enteric film properties through dry media reaction, Eur. J. Pharm. Biopharm., 70 (2008) 335-344.

DOI: 10.1016/j.ejpb.2008.03.002

Google Scholar

[5] S. Soradech, J. Nunthanid, S. Limmatvapirat, M. Luangtana-anan, An approach for the enhancement of the mechanical properties and film coating efficiency of shellac by the formation of composite films based on shellac and gelatin, Journal of Food Engineering, 108 (2012) 94-102.

DOI: 10.1016/j.jfoodeng.2011.07.019

Google Scholar