Preparation and Optimization of a Live Newcastle Disease Virus Vaccine Encapsulated in Chitosan Nanoparticles

Yan Hao; Hao Wu; Wei Li; Xiao Mei Luo; Kai Zhao

doi:10.4028/www.scientific.net/AMR.662.149

Paper Titles

Carbon Nanotubes Supported Pt Catalysts for Ethanol Oxidation in Alkaline Solutions
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Copolymer Nanoparticles Prepared by Self-Assembly of Poly(ethylene glycol) and Poly-γ-Glutamic Acid and its Characteristics
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Effects of DTAB on Performance of Nano Pd/C Catalyst for Purification of Terephthalic Acid
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Investigation on Viscosity of Carbon Nanofibers Reinforced Epoxy
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Preparation and Optimization of a Live Newcastle Disease Virus Vaccine Encapsulated in Chitosan Nanoparticles
p.149

Preparation of Nano Pd/C Catalyst for Purification of Terephthalic Acid by Sol-Gel Method
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Research on Reaction Kinetics of Photocatalytic Degradation of Methylene Blue in Water Solution with SrTiO₃ Nano Film
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Study on Photocatalytic Performance of Ag - AgBr/RGO
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Application of Nano- TiO₂ Used in Road Engineering and its Long-Term Decomposition Effect
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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 662Preparation and Optimization of a Live Newcastle...

Preparation and Optimization of a Live Newcastle Disease Virus Vaccine Encapsulated in Chitosan Nanoparticles

Abstract:

In this study, the researcher’s interest is focused on establishing a model with La Sota live vaccine immobilized into chitosan, which was prepared using a ionic gelation method. The formulation, preparation procedure, influence factors, physicochemical characteristics were evaluated. The results of study demonstrate that the NDV-CS-NPs have been produced with suitable size, morphous regulation, extremely spherical shape, regular and well-distributed. The NDV-CS-NPs produced by the optimal formulation were average size (371.1nm) and proper zata potential (+2.84 mV). The entrapment efficiency was (74±3.7) %. It can provide a new useful information for the development and evaluation of synthetic vaccines.

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Periodical:

Advanced Materials Research (Volume 662)

Pages:

149-152

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.662.149

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Online since:

February 2013

Authors:

Yan Hao, Hao Wu, Wei Li, Xiao Mei Luo, Kai Zhao

Keywords:

Chitosan, Nanoparticle, NDV, Preparation

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