Antitumor Activity of Porcine Cartilage Polysaccharide on Breast Cancer

Jing Jing Fang; An Jun Liu; Zhen Yuan Zhu; An Guo Teng; Guo Qiang Zheng; Wen Hang Wang; Qi Rong; Yu Gang Qi

doi:10.4028/www.scientific.net/AMR.716.451

Paper Titles

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Convergent Synthesis of Polyimide Dendrimers from an ABB' Intermediate
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Experimental Research on the Predictive Model for Surface Roughness of Titanium Alloy in Abrasive Belt Grinding
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Antitumor Activity of Porcine Cartilage Polysaccharide on Breast Cancer
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Microencapsulation of Rutin in Chitosan-Coated Alginate Microspheres through Internal Gelation Technique
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Evaluation of Mercury Contamination in Surface Sediments of Southern Kaohsiung Harbor, Taiwan
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Mutual Symbiotic Methanogenic Process between Acetotrophic and Hydrogenotrophic Methanogens during Anaerobic Digestion
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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 716Antitumor Activity of Porcine Cartilage...

Antitumor Activity of Porcine Cartilage Polysaccharide on Breast Cancer

Abstract:

The antitumor activity of porcine cartilage polysaccharide was evaluated by vivo animal models. The Ca761 tumor-bearing mice were treated with daily intraperitoneal injections of normal saline (control group) or cartilage polysaccharide (1500, 3000 or 4500mg/kg CPS group) for 14 days. The results demonstrated that CPS could effectively inhibit the tumor growth in Ca761 tumor-bearing mice. The tumor weights of the CPS groups were smaller compared to the control group. While the thymus index, spleen index were higher in the high dose 4500mg/kg CPS group than the control group. These results suggest that CPS might be a strong natural immunomodulator and the antitumor effect of this polysaccharide is associated with its potent immunostimulating effect.

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Periodical:

Advanced Materials Research (Volume 716)

Pages:

451-454

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.716.451

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Online since:

July 2013

Authors:

Jing Jing Fang, An Jun Liu, Zhen Yuan Zhu, An Guo Teng, Guo Qiang Zheng, Wen Hang Wang, Qi Rong, Yu Gang Qi

Keywords:

Antitumor, Ca761 Breast Cancer Cells, Cartilage Polysaccharide

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