The Ion Chromatography Intergrated Amperometry Method to Detectsulfonamides

Abstract:

In this study, the high performance ion chromatography integrated pulsed amperometric detection (HPIC-IPAD) was appliedfor the first time to detect 10 sulfonamides. In this experiment,we used Dionex AS18 (250mm×2mm) and AG18 (50mm×2mm) columnsfilled with an anion exchange resin, with 14 mmol / L NaOH solution concentration. The Analysis temperature was 30 ° C, the flow rate was 0.25 mL / min, and the injection volume was 10 μL. The detection was through pulsed amperometric detection cell with Au electrode and reference electrode pH-Ag/AgCl as working electrodes. Take the standard stock solution compounding 0.06,0.15,0.30,1.5,3.0 mg / L standard solutions respectively,build linear regression on chromatographic peak area as Y and analyte mass concentration of as X (mg / L). In the range of 0.06-3.0 mg / L, the 10 sulfonamides response appeared a linear relationship (R> 0.9989). This method can be considered for the detection of trace sulfonamides substances in cosmetics, food, and feed.

• Periodical: Advanced Materials Research (Volumes 726-731)
• Pages: 1544-1547
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.726-731.1544
• Online since: August 2013
• Authors: Wei De Lu, Zhan Qing Ma, Jun Feng Rao
• Keywords: Amperometric Detection, Ion Chromatography, Sulfonamide

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