Feasibility Study of Photoacoustic Imaging for Monitoring Temperature in Photothermal Therapy

Yu Bin  Liu; Zhi Fang Li; Wen Ming Xie; Hui Li; Wei R.  Chen; Hai Yu  Chen

doi:10.4028/www.scientific.net/AMR.760-762.872

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 760-762Feasibility Study of Photoacoustic Imaging for...

Feasibility Study of Photoacoustic Imaging for Monitoring Temperature in Photothermal Therapy

Abstract:

Photothermal therapy relies on the principle of converting light energy into heat causing localized lesion destruction. For safe and effective treatment, it is necessary to monitor temperature diffusion in the boundaries of the irradiated region, to minimize damage to surrounding normal tissues. This paper gives a pilot study of the feasibility of photoacoustic imaging for monitoring temperature changes during photothermal therapy. The results showed that our system of photoacoustic imaging (PAI) can play the role of biosensor, for the photoacoustics signal amplitude depend on temperature of tissue-mimicking phantoms. Whats more, photoacoustic signal can determinate the boundary of photoabsorder-enhance tissue during therapeutic procedure.

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Periodical:

Advanced Materials Research (Volumes 760-762)

Pages:

872-875

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.760-762.872

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Online since:

September 2013

Authors:

Yu Bin Liu, Zhi Fang Li, Wen Ming Xie, Hui Li, Wei R. Chen, Hai Yu Chen

Keywords:

Photoacoustic Imaging, Photothermal Therapy, Saturation Absorption, Temperature

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