Synthesis of Oil-Soluble Aliphatic Acylated Epicatechin and their Free Radical Scavenging Activity

Abstract:

A series of epicatechin derivatives, including 3-O-palmitoyl epicatechin, 3-O-myristoyl epicatechin, 3-O-lauroyl epicatechin, 3-O-decanoyl epicatechin and 3-O-octanoyl epicatechin, were prepared by the acylation method. Structures of these prepared products were characterized by LC/MS and ¹H-NMR spectroscopy. Their antioxidant activity were assessed by the methods of DPPH and ABTS free radical scavenging. The results showed that aliphatic acyl epicatechin derivatives with varying aliphatic groups were synthesized by this method. The antioxidant activity of aliphatic acyl epicatechin derivatives were better than the oil-soluble tea polyphenol and BHT, equal to TBHQ.

• Periodical: Advanced Materials Research (Volumes 781-784)
• Pages: 1424-1429
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.781-784.1424
• Online since: September 2013
• Authors: Zhe Gao, Yu Lei Pan, Ai Xia Qin, Xiao Hu Kang, Xi Yue Li, Ya Nan Jia, Can Chen, Tong Cui
• Keywords: 3-O-aliphatic Acyl Epicatechin, Acylation Reaction, Epicatechin, Free Radical Scavenging Activity, Oil-Soluble Antioxidants

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