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Extraction, Purification and Cytotoxic Activity of Cerebrosides from Asterina pectinifera

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Abstract:

Cerebrosides were extracted from Asterina pectinifera using ethanol extraction and silica gel column chromatography. The identification of the cerebrosides was established based on thin layer chromatography (TLC), UV, IR and HRMS. The cerebrosides exhibited moderate cytotoxic activities against Hela and BEL7402 cell lines. At the concentration range of 10-400μg/ml, cytotoxicity of cerebrosides on two human tumor cells showed a dose-and time-dependent manner.

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Periodical:

Advanced Materials Research (Volumes 781-784)

Pages:

682-686

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.781-784.682

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Online since:

September 2013

Authors:

Hai Jiao Zuo, Tian Wang, Yan Xia Qi, Qian Cheng Zhao, Zhi Bo Li

Keywords:

Asterina pectinifera, Cerebrosides, Cytotoxic Activity, Extraction, Purification

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© 2013 Trans Tech Publications Ltd. All Rights Reserved

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