Extraction, Purification and Cytotoxic Activity of Cerebrosides from Asterina pectinifera

Hai Jiao Zuo; Tian Wang; Yan Xia Qi; Qian Cheng Zhao; Zhi Bo Li

doi:10.4028/www.scientific.net/AMR.781-784.682

Paper Titles

Study on Extraction Process and Content Determination of Safflor Yellow
p.663

Protective Effects of Gynostemma pentaphyllum Makino Polysaccharide on Alcoholic Hepatic Injuries
p.668

Eco-Friendly of Hibiscu cannabinus L. Fibers Dyeing with Natural Dye
p.674

Preliminary Researches on Influence of Several Kinds of Plants Including Ajuga Ciliata Bunge on Activity of Cholinesterase from Pig Serum
p.678

Extraction, Purification and Cytotoxic Activity of Cerebrosides from Asterina pectinifera
p.682

Optimization of Ultrasonic-Assisted Extraction of Total Saponins from Ophiopholis mirabilis Using Response Surface Methodology
p.687

A Bio-Material of Polymer Beads Based on Antibody Immobilization via Oxidized Glycochains Linkage for Flow Cytometric Suspension Array
p.694

Immunolocalization and Correlation Frequencies of Lingual Antimicrobial Peptide and Lactoferrin in Bovine Alveolar Epithelium and Bovine Mammary Gland
p.699

The Effects of Strains Inoculation Amount on the Degree of Hydrolysis of Fermented Tilapia Scraps Mixed with Soybean Meal
p.711

HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 781-784Extraction, Purification and Cytotoxic Activity of...

Extraction, Purification and Cytotoxic Activity of Cerebrosides from Asterina pectinifera

Abstract:

Cerebrosides were extracted from Asterina pectinifera using ethanol extraction and silica gel column chromatography. The identification of the cerebrosides was established based on thin layer chromatography (TLC), UV, IR and HRMS. The cerebrosides exhibited moderate cytotoxic activities against Hela and BEL7402 cell lines. At the concentration range of 10-400μg/ml, cytotoxicity of cerebrosides on two human tumor cells showed a dose-and time-dependent manner.

You might also be interested in these eBooks

View Preview

Info:

Periodical:

Advanced Materials Research (Volumes 781-784)

Pages:

682-686

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.781-784.682

Citation:

Cite this paper

Online since:

September 2013

Authors:

Hai Jiao Zuo, Tian Wang, Yan Xia Qi, Qian Cheng Zhao, Zhi Bo Li

Keywords:

Asterina pectinifera, Cerebrosides, Cytotoxic Activity, Extraction, Purification

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

References

[1] Rumiana K, Martin C: Phases and phase transitions of the sphingolipids. BBA, Vol. 1255 (1995), pp.213-236.

Google Scholar

[2] A. G. Guzii, T. N. Makarieva, V. A. Denisenko, a V. I. Svetashev, S. A. Rodkina, P. S. Dmitrenok, S. D. Anastyuk and V. A. Stonika: Russian Chemical Bulletin Vol. 55, No. 5, pp.928-933.

DOI: 10.1007/s11172-006-0354-4

Google Scholar

[3] Xiaojun Liu, Wutong Wu: Pharmaceutical Biotechnology, In Chinese, Vol. 23, No. 3 (1995), pp.19-23.

Google Scholar

[4] Zengqi Liu, Tao Jing.: Tianjin Medicine, In Chinese, Vol. 15, No. 4, (2003), pp.64-67.

Google Scholar

[5] Yisu Sang, Zhida Min: Chinese Journal of Biochemical Pharmaceutics, In Chinese, Vol. 21, No. 4 (2000), 211-213.

Google Scholar

[6] Yingtao Lv, Congmin Kang, Changhu Xue: Food Science, In Chinese, Vol. 30, No. 11 (2009), pp.26-28.

Google Scholar

[7] Yamada K, Sasaki K, Harada R, et a1.: Chemical&Pharmaceutical Bulletin Vol. 50 (2002), pp.1467-1470.

Google Scholar

[8] Jin WZ, Kenneth LR, Elizabeth A: J Org Chem Vol. 59 (1994), pp.144-147.

Google Scholar

[9] Fatttorusso E, Mangoni A: Progress in the chemistry of natural products, edtied by Springer Wien, New York, No. 72 (1997), pp.215-301.

Google Scholar

[10] Natori T, Morita M, Akimoto K, et al.: Tetrahedron Vol. 50, No. 9 (1994), pp.2771-2784.

Google Scholar

[11] Wang LP, Wang T, Fehr W: Journal of Agriculture and Food Chemistry, Vol. 54 (2006), pp.7812-7816.

Google Scholar

[12] Zhao, G. H., Kan, J. Q., Li, Z. X., & Chen, Z. D: Carbohydrate Polymers, Vol. 61 (2005), pp.125-131.

Google Scholar

[13] Mosmann T: J Immunol methods, Vol. 65 (1983), p.55.

Google Scholar