Study on the Preparation of Repaglinide Chitosan Microspheres with Genipin

Yue Zhang; Xian Xian Shi; Yi Feng Yu; Yong Xing Song

doi:10.4028/www.scientific.net/AMR.791-793.252

Paper Titles

Spectroscopic Analysis on the National-Level Combination Medicine Biqi Capsule
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Morphology and Crystallization Behavior of Toughened Poly(Trimethylene Terephthalate) Blends with Acrylonitrile-Butadiene-Styrene
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Development and Analysis of Aroma Compounds of Low Alcohol Blue Berry Wine
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Preparation and Properties of the Novel Adsorbent Agent for Juices Clarification
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Study on the Preparation of Repaglinide Chitosan Microspheres with Genipin
p.252

Effect of Organoclay on Thermal Degradation and Crystalline Morphology Properties of Biodegradable PHBV
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Investigation on Thermal Decomposition Kinetics of Ulipristal Acetate (Form B)
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Pre-Processing Influence on Identification of Optimal Path Length for NIR Analysis of Tea Polyphenols
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Combinatorial Screening of COX-2 Inhibitors from Chinese Herbs Based on Multiple Structure-Based Pharmacophores
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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 791-793Study on the Preparation of Repaglinide Chitosan...

Study on the Preparation of Repaglinide Chitosan Microspheres with Genipin

Abstract:

In this paper, the repaglinide chitosan microsphere crosslinked with genipin was prepared by emulsification-chemical crosslinking method, and chitosan is used as coating materials, genipin as a crosslinking agent, repaglinide as active agent, span-80 as emulsifier. The prepared microspheres were also characterized by SEM, IR and DSC. The encapsulation efficiency of repaglinide microsphere was 4.4% and the drug loading was 21.9%.