Highly-Efficient Preparation of Key Intermediate of Huperzine A

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Abstract:

Huperzine A was approved for curing Alzheimers disease in the early 1990s in China. We explored a highly-efficient synthetic route for the key intermediate in the total synthesis of this natural product. Only common reagents and conditions were involved. So our new route has potential application in large-scale preparation of the key intermediate.

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181-184

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September 2013

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© 2013 Trans Tech Publications Ltd. All Rights Reserved

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