On the Determination of Content of 10 - DABIII in Enshi’s Taxus Chinensis Var Mairei

Article Preview

Abstract:

Chemical semi-syntheticmethod for efficient low toxicity of paclitaxelanalogues is the hot issue quite a longtime in the present and the future of chemical, biological medicine and relatedinterdisciplinary researches. 10-DABIII is the main precursor semi-syntheticraw materials. Taking Enshi’s perennial natural taxus chinensis and taxuschinensis leaves of artificial cultivation as raw material to study the effectof different drying methods and extraction methods on the contents of 10-DABIII.Experimental results show that the 10-DABIII in the natural taxus chinensis ishigher than that of artificially cultivated taxus chinensis; different dryingmethods affect the amount of 10-DABIII, that is, by contrast, drying processingmethod in 50°Clow temperature is superior to drying in the shade of the nature, and microwaveextraction is more efficient than conventional solvent one. Knowing the contentof 10-DABIII in Enshi’s taxus chinensis can provide the necessary experimentaldata for rational utilization of taxus chinensis medicinal material resources, topromote Enshi’s local economic development.

You might also be interested in these eBooks

Info:

Periodical:

Advanced Materials Research (Volumes 821-822)

Pages:

1055-1059

Citation:

Online since:

September 2013

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2013 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] X.G. Mei, M.B. Lu: Foreign Medical Sciences (Section of Pharmarcy) Vol. 23 (1996) No. 3, pp.136-140 (In Chinese).

Google Scholar

[2] H. Zhou D.H. Chen, H.W. Gao and Q.G. Li: Letters in Organic Chemistry Vol. 7(2010) No. 6, pp.450-452.

Google Scholar

[3] D.F. Hong, W.M. Zhou, L.L. Li, H.D. Ma and R.S. Li: Acta Agriculturae Boreali-occidentalis Sinica, Vol. 16 (2007) No. 5, pp.227-230.

Google Scholar

[4] Q.W. Fan: Synthesis and Technology of Taxol C-13 Side Chain (MS., Nanjing University of Science and Technology, China 2010), p.10.

Google Scholar

[5] X. Feng, Z.M. Zou, Z.Y. Chu and D.A. Sun: Chinese Journal of Natural Medicines, Vol. 9 (2011) No. 6, pp.466-472.

Google Scholar

[6] Z.M. Du, R.L. Chen and F.Q. Liu: Chinese Traditional and Herbal Drugs, Vol. 35 (2004) No. 4, pp.398-399.

Google Scholar