In Vitro Cytotoxicity of PET-Based Hollow Fibers Containing Silver Particles on Hela Cells

Ling Lin; Hui Gai Li; Mei Zhen Wang; Xuan Wang; Shan Yuan Wang

doi:10.4028/www.scientific.net/AMR.821-822.3

Paper Titles

Preface and Conference Organization

In Vitro Cytotoxicity of PET-Based Hollow Fibers Containing Silver Particles on Hela Cells
p.3

Preparation of Optical Reflective Fiber with Transparent Nylon
p.7

Dissolving Approach of Cellulose and its Application in Producing Cellulose Functional Material
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Plasma Modification of Kapok Fiber and its Properties
p.18

Effect of Processing Conditions on Properties of KMnO₄-Treated PAN Fibers
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Effect of Honeysuckle Extract for Color Protection of Human Hair Exposed to Sunlight Radiation
p.28

Effect of Process Parameters on Continuous Nanofiber Yarn Using Two Oppositely Charged Spinnerets
p.32

Mass Production of Nanofibers from a Spiral Coil
p.36

HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 821-822In Vitro Cytotoxicity of PET-Based Hollow Fibers...

In Vitro Cytotoxicity of PET-Based Hollow Fibers Containing Silver Particles on Hela Cells

Abstract:

This work focuses on cellular toxicity of PET-based hollow fiber containing silver particles (Ag/PET hollow fiber), which was synthesized by different pressure method. Hela cells were used to investigate in vitro cytotoxicity of Ag/PET hollow fiber with the method of Methyl Thiazolyl Tetrazolium (MTT) assay. And the results showed no significant toxicity to Hela cells. And the SEM images of Hela cells treated by Ag/PET hollow fibers showed that cells morphology was unaltered in the present of Ag/PET hollow fiber. However, abnormal size, shrinkage and rounded appearance of cells at higher dose (20mg/ml)suggested slight toxicity of Ag/PET hollow fiber. Combining the antibacterial concentration (37.5μg/ml) in the pre-works, it was found that there was a certain concentration of silver ions which can achieve a minimization of cytotoxicity and a maximization of antibacterial efficacy.

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Periodical:

Advanced Materials Research (Volumes 821-822)

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3-6

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.821-822.3

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Online since:

September 2013

Authors:

Ling Lin*, Hui Gai Li, Mei Zhen Wang, Xuan Wang, Shan Yuan Wang

Keywords:

Cytotoxicity, Hela Cells, Hollow Fiber, Silver Particles

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