Design and Fabrication of Customised Scaffold for Femur Bone Using 3D Printing

Abstract:

Additive Manufacturing is a promising field for making three dimensional scaffolds in which parts are fabricated directly from the 3D CAD model. This paper presents, the patients CT scan data of femur bone in DICOM format is exported into MIMICS software to stack 2D scan data into 3D model. Four layers of femur bone were selected for creation of customised femur bone scaffold. Unit cell designs such as double bend curve, S bend curve, U bend curve and steps were designed using SOLIDWORKS software. Basic primitives namely square, hexagon and octagon primitives of pore size 0.6mm, 0.7 mm and 0.8 mm diameter and inter distance 0.7mm, 0.8mm and 0.9 mm are used to design the scaffold structures. In 3matic software, patterns were developed by using the above four unit cells. Then, the four layers of bone and patterns were imported into 3matic to create customised bone scaffolds. The porosities of customised femur bone scaffold were determined using the MIMICS software. It was found that the customised femur bone scaffolds for the unit cell design of U bend curve with square primitives of pore size 0.8mm diameter and inter distance 0.7mm gives higher porosity of 56.58 % compared to other scaffolds. The models were then fabricated using 3D printing technique.

• Periodical: Advanced Materials Research (Volume 845)
• Pages: 920-924
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.845.920
• Online since: December 2013
• Authors: V. Iraimudi*, S. Rashia Begum, G. Arumaikkannu, R. Narayanan
• Keywords: Additive Manufacturing (AM), Bone Scaffold, MIMICS, Pore Size, Porosity

References

[1] ASTM F2792-10. Standard Terminology for Additive Manufacturing Technologies, copyright ASTM International, 100 Barr Harbor Drive, West Conshohocken, PA 19428. www. astm. org.

[2] Chua CK, Leong KF, Cheah CM, Chua SW. Development of a tissue engineering scaffold structure library for rapid prototyping. Part 1: investigation and classification. Int J Adv Manuf Technol 2003; 21: 291–301.

DOI: 10.1007/s001700300034

[3] Hutmacher DW, Sittinger M, Risbud MV. Scaffold-based tissue engineering: rationale for computer-aided design and solid free-form fabrication systems. Trends Biotechnol 2004; 22(7): 354–62.

DOI: 10.1016/j.tibtech.2004.05.005

[4] J. W. Halloran, V. Tomeckova, S. Gentry et al., Photopolymerization of powder suspensions for shaping ceramics, Journal of the European Ceramic Society, vol. 31, no. 14, p.2613–2619, (2011).

DOI: 10.1016/j.jeurceramsoc.2010.12.003

[5] Cooper, Rapid Prototyping Technology, Marcel Dekker, (2001).

[6] Chu TMG. Hollister SJ, Feinberg SE, 2001. Hydroxyapatite implants with design internal architecture. Journal of Materials science: Materials in Medicine 12, 471-478.

[7] Yang S F, bong K F, Du Z H, Chua C K., 2001. The design of scaffolds for use in tissue engineering. Tissue Engineering 7(6), 679-689.

DOI: 10.1089/107632701753337645