Preparation of Silk Fibroin/Gelatine Blend Nanofibresby Roller Electrospinning Method

Abstract:

This study was focused on the preparation of electrospunnanofibres from silk fibroin (SF)/gelatin (GP) blends solution using a roller electro spinning method. The effects of mixing ratio in SF/GP blend solution on properties of spinning solution (e.g., viscosity, conductivity and surface tension) and morphology of electrospunfibres were studied. The SF/GP blends solution containing up to the gelatin content of 30% could be electro spun into the continuous fibrous structure. Average diameter of SF/GP electrospunfibres were increased by increasing the amount of gelatin in spinning solution. The SF/GP electrospunfibres showed bigger diameter and broader diameter distribution than pure silk fibroin electrospunfibres. The SF/GP nanofibres had diameters ranging from 400 to 1300 nm.

• Periodical: Advanced Materials Research (Volume 849)
• Pages: 45-49
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.849.45
• Online since: November 2013
• Authors: Nongnut Sasithorn, Lenka Martinová
• Keywords: Gelatin, Nanofiber, Roller Electro Spinning, Silk Fibroin

References

[1] Amiraliana, N.; Nouri, M.; Kishb, M.H.: An Experimental study on Electrospinning of silk fibroin, http: /www. docstoc. com/docs/26292086. Accessed: 2011-05-02.

[2] Nerem R.M.; Sambanis A.: From Biology to Biological Substitutes, Tissue Engineering, Vol. 1 (2007), pp.3-13.

[3] Stankus J.J.; Soletti L.; Fujimoto K.: Fabrication of Cell Microintegrated Blood Vessel Constructs Through Electrohydrodynamic Atomization, Biomaterials, Vol. 28 (2007), pp.2738-2746.

DOI: 10.1016/j.biomaterials.2007.02.012

[4] Zhanga, X.; Khanb M.R.; Yamamoto,T.; Tsukada, M. Morikawa, H.: Fabrication of silk sericin nanofibers from a silk sericin-hope cocoon withelectrospinning method, International Journal of Biological MacromoleculesVol. 50 (2012) , pp.337-347.

DOI: 10.1016/j.ijbiomac.2011.12.006

[5] Lukáš, D.; Sarkar A.; Martinová, L.; Vodsedálková, K.; Lubasová, D.; Chaloupek, J.; Pokorný, P.; Mikeš, P.; Chvojka, J. & Komárek M.: Physical principles of electrospinning (Electrospinning as a nano-scale technology of the twenty-first century), Textile Progress, Vol. 41 (2009).

DOI: 10.1080/00405160902904641

[6] Niu, H.; Wang, X. Lin, T.: Needleless Electrospinning : Developments and Performances, http: /cdn. intechopen. com/pdfs/23290/InTech-Needleless_electrospinning_developments_andperformances. pdf. Accessed: 2012-05-16.

DOI: 10.5772/24999

[7] Veparia, C.; Kaplana D.L.: Silk as a biomaterial, Progress in Polymer Science, Vol. 32 (2007) pp.991-100.

[8] Amiraliana, N.; Nouri, M.; Kishb, M.H.: Effects of Some Electrospinning Parameters on Morphology of Natural Silk-Based Nanofibers, Journal of Applied Polymer Science, Vol. 113 (2009) pp.226-234.

DOI: 10.1002/app.29808

[9] Tofoleanu F.; Balau Mindru T.; Brinza F. Sulitanu N.; Sandu I. G.; Raileanu D.; Floristean V.; Hagiu B. A.; Ionescu C.; Sandu I.; Tura V.: Electrospun Gelatin NanofibersFunctionalized With Silver Nanoparticles, Journal of optoelectronics and advanced materials, Vol. 10 (2008).

[10] Armato,U.;, Pra, I.D.; Migliaresi, C.; Motta, A,; Kesenci, K.: Method for the Preparation of a Non-Woven Silk Fibroin Fabrics. US Patent 7285637, October 23, (2007).

[11] Ramakrishna, S.; Fujihara, K.; Teo, W.E.; Lim, T.C.; Ma Z.: An Introduction toElectrospinningand Nanofibers, ISBN 981-256-415-2, World Scientific Publishing Co. Pte. Ltd., Singapore.

[12] Andrady, A.L.: Science and Technology of Polymer Nanofibers, John Wiley & Sons, Inc., ISBN 978-0-471-79059-4, the United States of America (2008).