Preparation and Performance of Controlled-Release Tablets of Sasanquasaponin-Sodium Alginate-Hydroxypropyl Methyl Cellulose

Xiao Zhou Liu; Xiao Zhen Liu; Zhong Fang Lai; Yue Xing Song; Li Zhai

doi:10.4028/www.scientific.net/AMR.884-885.494

Paper Titles

Optimization of Operation Parameters of Dry Anaerobic Co-Digestion from Animal Manure and Straw in a Batch Reactor
p.475

Physical Properties and Antimicrobial Activity of a Poly(Lactic Acid)/Poly(Trimethylene Carbonate) Film Incorporated with Thymol
p.481

Physicochemical Characteristics of Bacteriocin Produced by Pediococcus pentosaceus H6
p.485

Phytochemical Study and its Quantity and Quality of Fresh and Freeze-Dried Young Coconut Juice (Cocos nucifera L.)
p.490

Preparation and Performance of Controlled-Release Tablets of Sasanquasaponin-Sodium Alginate-Hydroxypropyl Methyl Cellulose
p.494

Prokaryotic Expression and Identification on the ag85a and mpb70 Fusion Gene of Mycobacterium bovis
p.498

Properties of Anaerobic Activated Sludge in Biohydrogen Production Reactor
p.503

Regression Analysis between Ash Content and Ultimate Analysis Indexes for Bio-Fuels from the Biomass Power Plant
p.507

Research on Attention EEG Based on Jensen-Shannon Divergence
p.512

HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 884-885Preparation and Performance of Controlled-Release...

Preparation and Performance of Controlled-Release Tablets of Sasanquasaponin-Sodium Alginate-Hydroxypropyl Methyl Cellulose

Abstract:

The controlled-release tablets of sasanquasaponin-sodium alginate-hydroxy-propyl methyl cellulose (SQS-SAL-HPMC) were prepared by using SQS, SAL and HPMC as the main drug and accessories. The effects of the preparation method of the controlled-release powder and the amount of ethanol on release rate respectively were studied. The release rate curve of the data of the prescription of the controlled-release tablets of SQS-SAL-HPMC were fitted as zero order, one order and Higuchi equation. The controlled-release tablet of SQS-SAL-HPMC was characterized by IR techniques. The releasing rate of the controlled-release tablets of SQS-SAL-HPMC are controlled by controlling the preparation method of the controlled-release powder and the amount of ethanol. The controlled- release tablets of SQS-SAL-HPMC release SQS by slowness and constant in 12h. The chemical bonds are formed among SQS, SAL and HPMC.

You might also be interested in these eBooks

Biotechnology, Chemical and Materials Engineering III

View Preview

Info:

Periodical:

Advanced Materials Research (Volumes 884-885)

Pages:

494-497

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.884-885.494

Citation:

Cite this paper

Online since:

January 2014

Authors:

Xiao Zhou Liu, Xiao Zhen Liu, Zhong Fang Lai, Yue Xing Song, Li Zhai

Keywords:

Controlled Release, Hydroxypropyl Methyl Cellulose, Release Rate, Sasanquasaponin, Sodium Alginate

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

References

[1] Z.F. Lai, Y.Z. Chen, J. Chen and X. Z Liu: Chinese Herbal Drug Research Trends. Nova Science Publishers, Inc. NY (2007), p.147.

Google Scholar

[2] Z.F. Lai, Z.Q. Shao, Y.Z. Chen, M. He: J. Pharmacol. Sci. Vol. 94 (2004), p.313.

Google Scholar

[3] Q.R. Huang, S.Y. Cao, M. He, P. Li and W.J. Peng: Chinese Journal of Clinical harmacology and Therapeutics. Vol. 8 (2003), p.170.

Google Scholar

[4] J. Chen, D. Liu and H.P. Chen: Chinese Pharm. Bulletin. Vol. 23 (2007), p.724.

Google Scholar

[5] Q.R. Huang, M. He and Y.C. He: Chinese Traditional and Herbal Drugs. Vol. 36(2005), p.1831.

Google Scholar

[6] P. Li, M. He and Q.R. Huang: Chinese Traditional and Herbal Drugs. Vol. 31(2000), p.841.

Google Scholar

[7] Q.R. Huang, Y.C. Dai, M. He and Y.M. Luo: Chinese Pharmacological Bulletin. Vol. 21 (2005), p.1092.

Google Scholar

[8] X.Z. Liu, J. Chen and Z.F. Lai: ZL200810042744. 4, 2008-9-11.

Google Scholar

[9] X.Z. Liu, R. Ran: Chinese Journal of Synthetic Chemistry. Vol. 5 (2008), p.611.

Google Scholar

[10] X.Z. Liu, L.L. Guo, L.L. Song and Z.F. Lai: Materiamedica. Vol. 20 (2009), p.3090.

Google Scholar

[11] X.Z. Liu, J.H. Yang, L.L. Song, Z.F. Lai and X.Q. Zhu: Spectroscopy and Spectral Analysis. Vol. 32 (2012), p.1650.

Google Scholar

[12] X.Z. Liu, L.W. Zhu, L.L. Song, Z.F. Lai, and W. Wu: Advanced Materials Research. Vol. 415 (2012), p.1713.

Google Scholar

[13] X.Z. Liu, J.H. Yang, Z.F. Lai, L.L. Guo, L.L. Song and Y.Q. Bi: Advanced Materials Research. Vol. 396 (2012), p.1684.

Google Scholar

[14] X.Z. Liu, Y.X. Song, Z.F. Lai, L.L. Guo and L.L. Song: Advanced Materials Research. Vol. 413 (2012), p.304.

Google Scholar

[15] State Pharmacopoeia Commission: Chinese Pharmacopoeia, 2005 edition. Chemical Industry Press. Beijing (2005).

Google Scholar