Application of Different Biomaterials in Achilles Tendon Repair for Exercise Injury

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Abstract:

The rupture of Achilles tendon is hard to self-healing and repair and it is easily left pain and dysfunction. For a long time, the treatment of Achilles tendon defect by many scholars conducted a lot of research, from the tendon autograft, allograft tendon transplantation to the artificial tendon transplantation, tissue engineering tendon transplantation. Practice has proved that these methods have their own advantages and disadvantages. Although the research and application of scaffold materials for tendon tissue engineering has achieved some success, but the application materials or the presence of biocompatibility, degradation problems or have poor mechanical properties, machining molding defects, there is still a big gap between the ideal scaffold materials. This study evaluated the different biological materials in the repair of Achilles tendon injury in effect, provide a theoretical reference for the key to construct tissue engineered tendon is to find appropriate scaffold materials for tendon cell adhesion, growth and functional differentiation.

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329-332

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January 2014

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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[1] Tiffany L. Sarrafian, Hali Wang, Eileen S. Hackett, et al. Comparison of Achilles Tendon Repair Techniques in a Sheep Model Using a Cross-linked Acellular Porcine Dermal Patch and Platelet-rich Plasma Fibrin Matrix for Augmentation. The Journal of Foot and Ankle Surgery, Volume 49, Issue 2, March–April 2010, Pages 128-134.

DOI: 10.1053/j.jfas.2009.12.005

Google Scholar

[2] William R. Webb, Tina P. Dale, Alex J. Lomas, et al. The application of poly (3-hydroxybutyrate-co-3-hydroxyhexanoate) scaffolds for tendon repair in the rat model. Biomaterials, Volume 34, Issue 28, September 2013, Pages 6683-6694.

DOI: 10.1016/j.biomaterials.2013.05.041

Google Scholar

[3] Arnaud Suwalski, Hinda Dabboue, Anthony Delalande, et al. Accelerated Achilles tendon healing by PDGF gene delivery with mesoporous silica nanoparticles. Biomaterials, Volume 31, Issue 19, July 2010, Pages 5237-5245.

DOI: 10.1016/j.biomaterials.2010.02.077

Google Scholar

[4] Jonathan B Feibel, Brad L Bernacki. A review of salvage procedures after failed achilles tendon repair. Foot and Ankle Clinics, Volume 8, Issue 1, March 2003, Pages 105-114.

DOI: 10.1016/s1083-7515(03)00005-6

Google Scholar