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Application of Matlab Data Processing System in Research of Drug Microemulsion

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Abstract:

A new O/W microemulsion system for transdermal matrine delivery was developed in order to improve the skin permeability and solubility of matrine. Various factors were investigated including solubility of matrine,the skin permeability of matrine aiming to choose suitable surfactants, cosurfactants and oils. By drawing the pseudo-ternary phase diagrams, the basic prescription of microemulsion were determined. A simplex lattice experiment design was adopted to optimize the composition of microemulsions.The mathematical software Matlab be used to calculate the predicted values to determine the optimization of microemulsion formulation.

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Periodical:

Advanced Materials Research (Volumes 887-888)

Pages:

623-626

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.887-888.623

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Online since:

February 2014

Authors:

Hong Wei*, Gang Lu, Yi Chen Lu, Zheng Fu

Keywords:

Mathematical Software, MATLAB, Microemulsion, Simplex Lattice

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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