Effect of Electrical Potential on DPPC Liposome Lubrication for Artificial Joint

Article Preview

Abstract:

This study aimed at investigating positive and negative potential effect on phospholipid lubrication for artificial joint. Surface potentials of CoCrMo in saline were measured once per day for 1 week to simulate corrosion of implanted artificial joint. Both +250 mV and-250 mV were applied on CoCrMo. 2mg/ml DPPC liposome was fabricated to produce lipidic adsorption on CoCrMo. Friction tests were carried out on cartilage vs. CoCrMo and UHMWPE vs. CoCrMo. The results showed that superficial potential of CoCrMo in saline changed from-177 mV at 1st day to 133mV at 7th day. Lubrication performance of DPPC liposome without potential was declined gradually. Liposome@-250 mV sustained low friction coefficient of both tribopairs whereas liposome@+250 mV greatly increased friction coefficient of UHMWPE vs. CoCrMo from 0.041 to 0.076. It demonstrated that negative potential enhanced adsorption of DPPC liposome, and promoted its lubrication. In contrast, positive potential on CoCrMo due to corrosion deteriorated liposome lubrication.

You might also be interested in these eBooks

Info:

Periodical:

Pages:

156-160

Citation:

Online since:

April 2014

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2014 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] M. A. MacConaill, Journal of anatomy 1932, 66, 210.

Google Scholar

[2] J. Charnley, The lubrication of animal joints, presented at Symposium on biomechanics, 1959; J. Charnley, Triangle; the Sandoz journal of medical science 1960, 4, 175; W. H. Davis Jr, S. L. Lee, L. Sokoloff, Journal of biomechanical engineering 1979, 101, 185.

Google Scholar

[3] A. Maroudas, Research Report 2: Hyaluronic Acid Films, presented at Proceedings of the Institution of Mechanical Engineers, Conference Proceedings, 1966; P. S. Walker, D. Dowson, M. D. Longfield, V. Wright, Annals of the rheumatic diseases 1968, 27, 512.

Google Scholar

[4] P. R. Lewis, C. W. McCutchen, Nature 1959, 184, 1285.

Google Scholar

[5] V. C. Mow, S. C. Kuei, W. M. Lai, C. G. Armstrong, Journal of biomechanical engineering 1980, 102, 73.

Google Scholar

[6] J. R. Levick, The Journal of physiology 1979, 289, 69; V. C. Mow, W. M. Lai, Siam Review 1980, 22, 275; M. K. Kwan, W. Michael Lai, C. Van Mow, Annals of Biomedical Engineering 1984, 12, 537.

DOI: 10.1007/bf02371448

Google Scholar

[7] B. A. Hills, Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 2000, 214, 83.

Google Scholar

[8] R. Goldberg, A. Schroeder, Y. Barenholz, J. Klein, Biophysical Journal 2011, 100, 2403.

Google Scholar

[9] J. W. Dobbie, C. Hind, P. Meijers, C. Bodart, N. Tasiaux, J. Perret, J. D. Anderson, Rheumatology 1995, 34, 13; I. M. Schwarz, B. A. Hills, Rheumatology 1996, 35, 821.

DOI: 10.1093/rheumatology/34.1.13

Google Scholar

[10] V. Saikko, T. Ahlroos, Wear 1997, 207, 86.

Google Scholar

[11] B. Purbach, B. A. Hills, B. M. Wroblewski, Clinical orthopaedics and related research 2002, 396, 115; B. A. Hills, R. W. Crawford, The Journal of Arthroplasty 2003, 18, 499.

DOI: 10.1097/00003086-200203000-00020

Google Scholar