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Effect of Electrical Potential on DPPC Liposome Lubrication for Artificial Joint
Abstract:
This study aimed at investigating positive and negative potential effect on phospholipid lubrication for artificial joint. Surface potentials of CoCrMo in saline were measured once per day for 1 week to simulate corrosion of implanted artificial joint. Both +250 mV and-250 mV were applied on CoCrMo. 2mg/ml DPPC liposome was fabricated to produce lipidic adsorption on CoCrMo. Friction tests were carried out on cartilage vs. CoCrMo and UHMWPE vs. CoCrMo. The results showed that superficial potential of CoCrMo in saline changed from-177 mV at 1st day to 133mV at 7th day. Lubrication performance of DPPC liposome without potential was declined gradually. Liposome@-250 mV sustained low friction coefficient of both tribopairs whereas liposome@+250 mV greatly increased friction coefficient of UHMWPE vs. CoCrMo from 0.041 to 0.076. It demonstrated that negative potential enhanced adsorption of DPPC liposome, and promoted its lubrication. In contrast, positive potential on CoCrMo due to corrosion deteriorated liposome lubrication.
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156-160
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April 2014
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© 2014 Trans Tech Publications Ltd. All Rights Reserved
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