Synthesis, Characterization and Antibacterial Activity of Chitosan/TiO2 Microspheres

Wen Ying Qi; Sai Sai Chen; Dan Yang; Qin Long Li; Xiao Rong Wu; Yu Zhen Lai; Wen Qing Yin; Cheng Bing Yu

doi:10.4028/www.scientific.net/AMR.912-914.362

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 912-914Synthesis, Characterization and Antibacterial...

Synthesis, Characterization and Antibacterial Activity of Chitosan/TiO₂ Microspheres

Abstract:

In this study, chitosan (CS)/titanium dioxide (TiO₂) microspheres with different nanoTiO₂ content were obtained by suspension cross-linking technique and characterized by FT-IR and SEM. The strong peak of C=N stretching vibrations at 1641 cm^-1 were found which demonstrated that amino groups of CS reacted with aldehyde group of glutaraldehyde. SEM photographs showed that the CS/TiO₂ microspheres were spherical, and the size of the CS/TiO₂ microspheres ranging from 50 to 170 μm was analyzed with the software of Image J. The entrapment efficiency of the CS/TiO₂ microspheres was up to 67.7%. Compared with CS, CS/TiO₂ microspheres had better antibacterial activity against S. aureus and E. coli with a MIC value of 0.0125%.

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Periodical:

Advanced Materials Research (Volumes 912-914)

Pages:

362-365

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.912-914.362

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Online since:

April 2014

Authors:

Wen Ying Qi*, Sai Sai Chen, Dan Yang, Qin Long Li, Xiao Rong Wu, Yu Zhen Lai, Wen Qing Yin, Cheng Bing Yu

Keywords:

Antibacterial, Chitosan/TiO₂, Microsphere, Suspension Cross-Linking

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* - Corresponding Author

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