Effect of Nanonization on Physicochemical Properties of Centella asiatica Powders

M.Z. Borhan; R. Ahmad; Mohamad Rusop; Saifollah Abdullah

doi:10.4028/www.scientific.net/AMR.917.106

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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 917Effect of Nanonization on Physicochemical...

Effect of Nanonization on Physicochemical Properties of Centella asiatica Powders

Abstract:

Centella asiatica (C. Asiatica) contains asiatic acid as one of bioactive constituent that has the commercial medicinal value such as anticancer and also possess wound healing property. The ball milling process was carried out at 0.5, 4 and 8 hours. The effects of ball milling at different times were characterized using particles size analysis (Photon Correlation Spectroscopy) and Fourier Transform infra red (FTIR) Spectroscopy. The surface morphology was characterized by Field-Emission Scanning Electron Microscope (FESEM). As a result, smallest particles size by mean 279.5 nm was produced at a longest milling time (8 hr) and FTIR spectra shows there is no obvious change in the structure of C. asiatica nanopowders as compared to the micropowders. Centella asiatica nanopowders shows good extraction yield of asiatic acid with 5.5 μg/ml of yield but poor inhibition of DPPH as compared to micropowders.

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Advanced Materials Research (Volume 917)

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106-112

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https://doi.org/10.4028/www.scientific.net/AMR.917.106

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June 2014

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M.Z. Borhan*, R. Ahmad, Mohamad Rusop, Saifollah Abdullah

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