The Synthesis and Immune Identification of Bisphenol A Artificial Antigen

Long Xu; Li Xin Zhu; Fan Fan Yang; Ren Rong Liu; Meng Wei

doi:10.4028/www.scientific.net/AMR.955-959.1024

Paper Titles

Heavy Metal Distribution and Sources in Pineapple-Growing Agricultural Soil in Hainan Province, China
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Synthesis of Vitamin B₁₂ Artificial Antigen and Determination of Hapten Coupling Ratio
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The Nanofiltration Technology of Metoprolol in the Water Environment
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The Research and Application of Efficient Dust Control System for Whole-Rock Comprehensive Mechanization Driving Face
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The Synthesis and Immune Identification of Bisphenol A Artificial Antigen
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What Kind of Occupational Health Conditions can meet the Entry Requirements of China Lead-Acid Battery Industry
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A Research on Bactericidal Agent of Heterotrophic Bacteria in Cooling Water by Composite of Non-Oxidizing Biocide and Oxidizing Biocide
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Analysis of Chronic Diseases in Technology Universities Faculty
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Comprehensive Assessment of Heavy Metal Contamination in Greenhouse Vegetables and Topsoils
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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 955-959The Synthesis and Immune Identification of...

The Synthesis and Immune Identification of Bisphenol A Artificial Antigen

Abstract:

Bisphenol A (BPA) belongs to estrogenic substances, which influences the development of genital system in human being. In this paper, 4, 4-bis (4-hydroxyphenyl) valeric acid (BVA), a derivative of BPA, was chosen as the hapten to prepare artificial antigen. An active ester method was used for coupling BPA hapten with keyhole limpet hemocyanin (KLH) and ovalbumin (OVA). Both UV spectra and immunoassay indicated that the two kinds of artificial antigen BVA-KLH and BVA-OVA were synthesized successfully. The artificial antigen of BPA can be used to develop monoclonal antibody of anti-BPA.

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Periodical:

Advanced Materials Research (Volumes 955-959)

Pages:

1024-1027

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.955-959.1024

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Online since:

June 2014

Authors:

Long Xu, Li Xin Zhu, Fan Fan Yang, Ren Rong Liu*, Meng Wei

Keywords:

Active Ester Method, Artificial Antigen, Bisphenol A, BVA, UV Spectra

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