A Bioreactor for a Pulsatile Circulatory Culture System

Abstract:

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Bioreactor technology is a branched research area of tissue engineering. Dynamic culture environment mimicking in vivo pulsatile conditions could be achieved by bioreactor otherwise might not through static cultures. In this paper, we present a new type of pulse bioreactor which can provide arbitrary and easily adjustable circulatory flow conditions of 0 - 0.2 MPa pressure. The pulse amplitude range was 0 - 7%. The pulse frequency can be adjusted between 0 and 80 times/min. In addition, the new type of pulse bioreactor can be sterilized and dismantled easily. This bioreactor has been used in dynamic culture of assembled adipose derived stem cells (ADSCs) and shown promise in tissue engineering.

Info:

Periodical:

Advanced Materials Research (Volumes 97-101)

Edited by:

Zhengyi Jiang and Chunliang Zhang

Pages:

1952-1955

DOI:

10.4028/www.scientific.net/AMR.97-101.1952

Citation:

H. R. Xu et al., "A Bioreactor for a Pulsatile Circulatory Culture System", Advanced Materials Research, Vols. 97-101, pp. 1952-1955, 2010

Online since:

March 2010

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Price:

$35.00

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