Dissimilar joining of Ti-22Al-25Nb alloy and an α+β titanium alloy TC11 were carried out using electron beam process and linear friction process, respectively. The microstructure and tensile properties of the joints were investigated. The results show that both EBW and LFW could be adopted to the dissimilar joining of Ti-22Al-25Nb/TC11. The EB welded joint exhibits higher strength than that of the LF welded joint, due to the precipitation of O phase in the fusion zone of the former one. These results can be expected to be of great technical interest as basic data for the use of EBW or LFW in aerospace industry.