Biocompatibility Evaluation of Co-Ribbons Prepared by Melt-Spinning

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Abstract:

Ribbons of Co-base alloy were tested as biocompatible material at in vitro process to develop in the future an implant dental device. Regarding research on the effect of rapid solidification on Co-alloys, few or absent studies to date have been assessed for the evaluation of surfaces properties when the alloys are placed in contact with human mesenchyme stem cells (hMSC). The Co-based ribbons were prepared by rapid solidification process and its surface attached with human adipose-derived mesenchymal stem cells to determine it toxicity, cells viability, adhesive and proliferation of the cells. Experimental results showed that Co-based ribbons are non-toxic material with 80% of increased cellular adhesion and exhibited excellent biocompatibility.

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98-102

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June 2014

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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