Synthesis and Characterization of Hydroxyethyl Cellulose/Chitosan Incorporated with Cellulose Nanocrystal Biopolymers Network

Abstract:

Biopolymeric scaffold remains one of promising candidates in various applications, such as biomedicine, pharmaceuticals, smart packaging, and cosmetics, following its advantage of non-toxicity, safety, and sustainability in bioresources. In this study, hydroxyethyl cellulose (HEC)/ chitosan (CS) incorporated with cellulose nanocrystals (CNC) was fabricated by lyophilization technique, obtaining fine porous scaffolds structure. HEC (5 wt.%) and CS (0.1 wt.%) were prepared and blended at 50:50 ratios following the addition of CNC as nanofiller material at 1, 2 and 3 wt.%. All scaffolds were characterized by their physical, chemical, thermal, and mechanical properties via SEM, ATR-FTIR, DSC and UTM. The SEM results show HEC/CS/CNC with pore diameter ranging from 25 μm to 28 μm. The ATR-FTIR spectra indicates a broad peak of O-H stretching at 3382 cm⁻¹ to 3397 cm⁻¹, and C=O stretching of amide group in the range of1645cm⁻¹ to 1653 cm⁻¹. Mechanical testing of the samples showed increasing tensile strength with increased concentration of CNC, indicating the improved toughness of the samples. The DSC result indicates a slight decrease in glass transition and melting temperature. Overall, the HEC/CS/CNC was successfully fabricated into bioplymeric scaffolds and could be a potential substrate for biomedical application.

• Periodical: Advances in Science and Technology (Volume 143)
• Pages: 3-8
• DOI: https://doi.org/10.4028/p-K3lnXO
• Online since: March 2024
• Authors: Farah Hanani Zulkifli*, Sulaiman Khan, Siti Maznah Kabeb, Nurul Huda Mohamed Shah
• Keywords: Biopolymeric Scaffolds, Cellulose Nanocrystals, Chitosan

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