We introduce a case study of “high sphericity” and “high uniformity” generated through flame synthesis. Recently, cosmetics need to solve 1) UV-protective effect, 2) transparence, and 3) smooth-textured touch. However, the best recipe and usable evaluation methods are not established. This research is a result combined with a theoretical approach of flame formation process, and a strategic regional alliance of the “AIST” grant venture. A new manufacturing and evaluation method has been commercialized in the forms of a highly original cosmetics and a new evaluation device.