Nano-Based PSA Biosensors: An Early Detection Technique of Prostate Cancer

Abstract:

Prostate-specific antigen or PSA is a protein biomarker which is produced by the cells of prostate gland. The normal level of PSA in blood is often elevated in men with prostate cancer. In India, prostate cancer is one among the five, mostly cited cancer in men and it is getting increased by 1% every year. The screening test used for prostate cancer is the Prostate Specific Antigen test. The first PSA assay was determined in 1979. Most of the current techniques used for PSA detection are utilizing large analyzers, there by increased time and cost. Increased PSA levels can also because of prostatitis (inflammation of the prostate gland) or due to many other reasons. A proper technique to differential diagnose this disease is also an issue. The benchmark for the PSA level cannot be determined accurately. For this, various types of biosensors are used. This review journal is is trying to analyze variouus Nano-Biosensors used for early detection of PSA from blood in an early stage itself.

• Periodical: Journal of Biomimetics, Biomaterials and Biomedical Engineering (Volume 20)
• Pages: 87-98
• DOI: https://doi.org/10.4028/www.scientific.net/JBBBE.20.87
• Online since: June 2014
• Authors: Mansoor Ani Najeeb*, Sankaranarayana Pillai, Murthy Chavali
• Keywords: Biosensor, Prostate Cancer, PSA, Sol-Gel

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