The paper reports about different kind of sutures, their suitability and performance. An ideal suture should possess many characteristics such as - easy to handle, bio-compatibility, minimal tissue reaction, resistance to bacterial growth, adequate tensile strength and elasticity, knot security, strength loss versus healing rate of tissues. Selection of suture is often very complex for satisfying host of physical, mechanical and biological properties, and fulfilling contradictory requirements in varied applications. The paper develops an understanding about the selection of suture depending on the varied requirement. Past research work pertaining to the development of suture as reported in this paper, provides insight about the suitability of different surgical sutures and possible direction of future research.