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HomeJournal of Biomimetics, Biomaterials and Tissue...Journal of Biomimetics, Biomaterials and Tissue...Subject Specific Modelling of Electrical...

Subject Specific Modelling of Electrical Conduction in the Body: A Case Study

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Abstract:

Modelling of bioelectric phenomena in the human body poses unique problems compared to those encountered in other fields of engineering. Accurate definition of the physical domain and material properties is difficult due to geometrical complexity and uncertainty in tissue characterisation. A workflow is presented for finite element simulation of electric current in the body. This is illustrated through an application on a subject-specific cranial model for simulation of a cochlear implant. Operations required for the full workflow include: data acquisition, image registration and segmentation, material property assignment, numerical analysis, and visualisation. The case study described uses MRI imaging and diffusion tensor MRI for definition of the analysis domain and material properties with analysis conducted in ANSYS. Image registration and segmentation were accomplished using custom designed algorithms. Visualisation was achieved using a 24-bit red-green-blue colour scheme to represent directional vectors.

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Journal of Biomimetics, Biomaterials & Tissue Engineering Vol.10

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Periodical:

Journal of Biomimetics, Biomaterials and Tissue Engineering (Volume 10)

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43-53

DOI:

https://doi.org/10.4028/www.scientific.net/JBBTE.10.43

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Online since:

May 2011

Authors:

Howard Lau, Andrew John Ruys, P. Carter, Xiu Wang, Qing Li

Keywords:

Diffusion Tensor MRI, Electrical Conduction, Finite Element Analysis (FEA), Subject Specific Model

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© 2011 Trans Tech Publications Ltd. All Rights Reserved

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