Porous bioactive titanium implant was produced by plasma-spray method and succeeding chemical and thermal treatment. This porous titanium implant possess a porosity of 40% and complex interconnective porous structure. Mechanical property of porous titanium was characterized for compressive and 4-point bending properties, as well as compressive fatigue. Bone tissue response and biocompatibility of porous bioactive titanium implant was evaluated by in vivo osteoconductive model. Ultimate compression strength and bending strength were 280 and 101 MPa. Bone ingrowth showed significant increases in treated implant, while in these untreated porous titanium implant, bone ingrowth seemed to decrease with time. These results suggest that porous bioactive titanium is a candidate for clinical applications under load-bearing conditions.