Mechanical Behavior of PLA/HA Composite in Simulated Physiological Environment

Article Preview

Abstract:

Effects of bio-degradation on the mechanical properties of polylactic acid (PLA)/hydroxyapatite (HA) were evaluated using a newly designed three-point bending fixture in SBF chamber. The composite was found to be ductile and insensitive to cracks, which is totally different from its brittle behavior observed in conventional tests, in which the degraded samples are tested in air at room temperature. Initial bending modulus and strength of PLA/HA composite were 1.2 GPa and 43 MPa, respectively, which were lower than those tested under room conditions. After two weeks of immersion in vitro, both bending modulus and strength decreased by 40% and 57%, respectively. Their degradation rates were both higher than those in reports of previous researches. This work indicates the importance of evaluating mechanical behavior in simulated body environment.

You might also be interested in these eBooks

Info:

Periodical:

Key Engineering Materials (Volumes 288-289)

Pages:

231-236

Citation:

Online since:

June 2005

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2005 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] S. Higashi, T. Yamamuro, T. Nakamura et al.: Biomaterials Vol. 7 (1986), p.183.

Google Scholar

[2] A.R. Boccaccini, I. Notingher, V. Maquet et al.: J. Mater. Sci.: Mater. Med. Vol. 14 (2003), p.443.

Google Scholar

[3] H.H. Lu, S.F. El-Amin, K.D. Scott et al.: J. Biomed. Mater. Res. Vol. 64A (2003). p.465.

Google Scholar

[4] T. Furukawa, Y. Matsusue, T. Yasunaga et al.: J. Biomed. Mater. Res. Vol. 50 (2000), p.410.

Google Scholar

[5] T. Yasunaga, Y. Matsusue, T. Furukawa et al.: J. Biomed. Mater. Res. Vol. 47 (1999), p.412.

Google Scholar

[6] X.D. Guo, Q.X. Zheng, J.Y. Du et al.: Chi. J. Biomed. Eng. Vol. 20 (2001), p.23.

Google Scholar

[7] D.P. Quan, Z.J. Lu, S.P. Li et al.: Chi. J. Biomed. Eng. Vol. 20 (2001), p.485.

Google Scholar

[8] H.M. Kim, T. Miyazaki, T. Kokubo et al.: Key Eng. Mater. Vol. 192-195 (2001), p.47. (a) (b) (c) 9. T. Kasuga, Y. Ota, M. Nogami et al.: Biomaterials Vol. 22 (2001), p.19.

Google Scholar

[10] D.P. Quan, K.R. Liao, Z.J. Lu et al.: Fu He Cai Liao Xue Bao Vol. 17 (2000), p.114.

Google Scholar