This study aims at investigating the effect of the sliding speed and the applied load on the dry sliding wear behavior of thermally sprayed Ni-based self-flux alloy coating. Ni-based self-flux alloy powders were flame-sprayed onto a carbon steel substrate and then these coatings were heat-treated at temperature of 1000 oC. Dry sliding wear tests were performed using the sliding speeds of 0.2, 0.4, 0.6 and 0.8 m/s and the applied loads of 5, 10, 15 and 20 N. AISI 52100 ball (diameter 8 mm) was used as counterpart material. Wear behavior of Ni-based self-flux alloy coatings was studied using a scanning electron microscope (SEM) and energy dispersive X-ray spectroscopy (EDX). It was revealed that microstructure and wear behavior of the Ni-based self-flux alloy coatings were much influenced by the sliding speed and the applied load.