Characterization and Protein Adsorption Ability of Zinc, Iron and Magnesium Hydroxyapatite

Toru Tonegawa; Toshiyuki Ikoma; Tomohiko Yoshioka; Guo Ping Chen; Nobutaka Hanagata; M. Tanaka

doi:10.4028/www.scientific.net/KEM.361-363.187

Paper Titles

Development of Multisubstituted Apatites for Bone Reconstruction
p.171

The Role of Si Substitution into Hydroxyapatite Coatings
p.175

The Effect of Particle Morphologies on Mechanical Properties of Porous Hydroxyapatite Scaffold
p.179

In Vitro Synthesis of Calcium Nanoparticles Using the Protein Cage of Apoferritin
p.183

Characterization and Protein Adsorption Ability of Zinc, Iron and Magnesium Hydroxyapatite
p.187

Preparation and Characterization of Boron-Containing Hydroxyapatite
p.191

Regulating Size, Morphology and Dispersion of Nano-Crystallites of Hydroxyapatite by pH Value and Temperature in Microemulsion System
p.195

Mg-Free Precursors for the Synthesis of Pure Phase Si-Doped α-Ca₃(PO4)₂
p.199

Effect of Mg²⁺ Addition during HA Nanoparticles Synthesis Using Ultrasonic Irradiation
p.203

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Characterization and Protein Adsorption Ability of Zinc, Iron and Magnesium Hydroxyapatite

Abstract:

The adsorption properties of metal ions containing hydroxyapatite (Ca10(PO4)6(OH)2, HAp) were elucidated for the development of protein drug carrier. As-prepared metal ion containing HAp nanocrystal showed plate-like morphology with 10-20nm in length and 5-10nm in width. The metal ion containing HAp microparticles had higher specific surface area than the HAp microparticle. The adsorption amount per unit area of HAp showed higher than those of metal ion containing HAp. The adsorption behavior followed the Langmuir curves for each protein, indicating the monolayer adsorption. The loaded amount of proteins could be one of the most important properties for the application of drug delivery carrier.