Radiopaque Strategy for Bone Injectable Substitute

Serge Baroth; Xavier Bourges; Borhane H. Fellah; Guy Daculsi

doi:10.4028/www.scientific.net/KEM.361-363.39

Paper Titles

Influence of Ca₂P₂O₇ on Sintering Ability, Mechanical Strength and Degradability of β-Ca₃(PO₄)₂ Bioceramics
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Porous Biphasic and Triphasic Bioceramics Scaffolds Produced by Gelcasting
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Effect of Octacalcium Phosphate Ionic Dissolution Products on Osteoblastic Cell Differentiation
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Nanocristalline Hydroxyapatite for Bone Repair
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Radiopaque Strategy for Bone Injectable Substitute
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Synthesis Bone Mineral (SBM) for Osteoporosis Therapy: Part 1 - Prevention of Bone Loss from Mineral Deficiency
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Synthesis and Characterization of Mg-Containing Nano-Apatite
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Influence of Association Type of Bisphosphonates with Calcium-Deficient Apatite on Drug Release
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Optimisation of the Aqueous Precipitation Synthesis of Silicate-Substituted Hydroxyapatite
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HomeKey Engineering MaterialsKey Engineering Materials Vols. 361-363Radiopaque Strategy for Bone Injectable Substitute

Radiopaque Strategy for Bone Injectable Substitute

Abstract:

The purpose of this study ass to investigate the addition of round 80-200m granules shape radiopaque agents (RA) to synthetic Injectable Bone Substitute to improve contrast performance for minimal invasive surgery MIS. Composites were obtained by mixing BaSO4, Bi2O3, Lu2O3 or GdPO4 with calcium deficient apatite CDA which decompose during sintering process in BCP (60% HA, 40% β-TCP). Each composite was characterized: by XRD, FTIR. Biocompatibility was tested in vitro and in vivo in bony site (3 weeks implantation in rats). Primary results show that the suitable radiopaque BCP/RA composite (radiopacity intensity, biological responses) appeared to be BCP/Ba. Next works will complete the current studies on biological performance in association with different kind of resorbable injectable bone substitute as suspension, gel or calcium phosphate cements.

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Periodical:

Key Engineering Materials (Volumes 361-363)

Pages:

39-42

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.361-363.39

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Online since:

November 2007

Authors:

Serge Baroth, Xavier Bourges, Borhane H. Fellah, Guy Daculsi

Keywords:

Biphasic Calcium Phosphate (BCP), Bone Ingrowth, Radiopaque, Round Granules

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References

[1] O. Gauthier et al. (2005) Biomaterials 26, Issue 27: 5444-43.

Google Scholar

[2] M.P. Ginebra, et al. (2002) Biomaterials 23, Issue 8: 1873-82.

Google Scholar

[3] Catharina S. J. van Hooy-Corstjens et al. (2004) Biomaterials 25, Issue 13: 2657-67.

Google Scholar

[4] S.M. Kurtz et al. (2005) Biomaterials 26, Issue 17: 3699-712.

Google Scholar

[5] G. Daculsi, et al. (2005) ITBM-RBM 26, issue 3: 218-22 Figure 5: MOVAT Pentachrome staining (A/B/C/D) and polarized light (E) BCP/Ba BCP/Bi BCP/Lu BCP/Gd BCP/Ba E.

DOI: 10.1111/j.2041-1014.2010.00596.x

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