Biocompatibility of Titanium Based Implants with Diamond-Like Carbon Coatings Produced by Plasma Immersion Ion Implantation and Deposition
A great number of studies have shown that diamond-like carbon (DLC) coatings could be developed for orthopaedic implants, but few articles have been published about in vivo evaluation. In this study, DLC coatings were deposited on titanium alloy (Ti-13Nb-13Zr) implants using the plasma immersion implantation and deposition (PIII-D), and the in vivo biocompatibility of DLC coatings was evaluated into both muscular tissue and femoral condyles of rats. Results indicate that DLC coatings are biocompatible in vivo, and DLC-coated implants were observed directly bonding to bone without any intervening soft tissue layer.
Guy Daculsi and Pierre Layrolle
E.T. Uzumaki et al., "Biocompatibility of Titanium Based Implants with Diamond-Like Carbon Coatings Produced by Plasma Immersion Ion Implantation and Deposition", Key Engineering Materials, Vols. 361-363, pp. 677-680, 2008