Abstract: Aiming at the demand of remanufacturing mechanical parts fatigue life prediction, the main methods of fatigue life prediction are reviewed and summarized. The finite element and dynamics combined simulation method has been widely used at present, whose advantages are that it is suitable for most of the mechanical parts, and the forecast cycle is short, and it can be analyzed combining with the parts actual working condition, but the prediction accuracy depends on the comprehensive degree to the service condition. The experimental method is the most traditional method, and the fatigue life value obtained by the method is reliable, but the method is entirely depend on experience, and the cost of experiments is expensive, so the feasibility is bad. The fatigue life analysis method can lower the dependence on large number of experiments, but there is a great distance between the predicting fatigue life and actual fatigue life in working environment. The metal magnetic memory non-destructive testing method doesnt damage the testing objects, but the method is still in the stage of further research at present. Finally, taking the number of experiments, prediction cycle, prediction accuracy, prediction cost and the complex degree of the principle involved in the prediction process as evaluation indexes, the finite element and dynamics combined simulation method is the best fatigue life prediction method according to the score values of each method calculated by the quantitative scores based on the expert evaluation method.