A Study on Application of Making Porous Micro-Structural Aluminum Oxide Template by Anodic Aluminum Oxide Processing Technology in Cell Reproduction
This study employed the Anodic Aluminum Oxide (AAO) method twice for AAO processing to prepare neatly-arranged aluminum oxide film micro nano porous structure, and conducted experiments by adjusting different condition parameters (current, voltage, and temperature). The experimental results showed that voltage would directly affect the pore space and surface roughness of the aluminum oxide film. In addition, after anodic treatment, the positive and negative surfaces demonstrated varying degrees of roughness under the same conditions. In this study, the experiment of surface roughness impact on cell proliferation demonstrated that cell proliferation was better when surface roughness was in the range of 0.4 nm < Ra < 1.2 nm.
Jianhong Zhao, Masanori Kunieda, Guilin Yang and Xue-Ming Yuan
Y. J. Weng et al., "A Study on Application of Making Porous Micro-Structural Aluminum Oxide Template by Anodic Aluminum Oxide Processing Technology in Cell Reproduction", Key Engineering Materials, Vols. 447-448, pp. 356-360, 2010