The purposes of this study were to develop a novel material which was infused nanotechnology into electronics subjects to vocational high school students’with no background in nanotechnology. And then to investigate the cognitive load of them, after they learnedthenovel curriculum pattern. The researchers began todevelop a novel electricsmaterial which is consisted of four chapters includedseven sectionsby experts of electronics, nanotechnology and vocational education. Theexperimentswere conducted by using PPT pedagogy to teach the nanotechnology infused into electronicscourse between twodepartments ofvocational high schools. After four months and four times in one month experimental teaching, cognitive load scale questionnaireand K of KAP scale questionnairewere examined.Finally, the applications of this materialare illustrated that the performances of K scores weresignificant differencebetween electronic engineering department and information engineering department.